DBZ (Dibenzazepine)
DBZ (Dibenzazepine) is a dipeptidic γ-secretase inhibitor with IC50 of 2.6 nM and 2.9 nM in cell-free assays for APPL and Notch cleavage, respectively.
Trivial name | YO-01027 |
Catalog Number | S2711 |
Molecular Formula | C20H22N4O3S |
CAS# | 209984-56-5 |
Inchi | InChI=1S/C20H22N4O3S/c1-21-19(26)16-10-13(8-9-22-16)27-12-6-7-15-18(11-12)28-20(24-15)23-14-4-2-3-5-17(14)25/h6-11,14,17,25H,2-5H2,1H3,(H,21,26)(H,23,24)/t14-,17-/m1/s1 |
Inchi Key | ADZBMFGQQWPHMJ-RHSMWYFYSA-N |
SMILES | CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)NC4CCCCC4O |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/yo-01027.html |
Additional Information | https://file.selleck.cn/downloads/struct/YO-01027-chemical-structure-s2711.gif |