Entinostat (MS-275)

Entinostat (MS-275, SNDX-275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM in cell-free assays, compared with HDACs 4, 6, 8, and 10. Entinostat induces autophagy and apoptosis. Phase 3.

Price Not Available 50mg Entinostat (MS-275) Supplier Page
Trivial name SNDX-275
Catalog Number S1053
Molecular Formula C21H20N4O3
CAS# 209783-80-2
Inchi InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)
Inchi Key INVTYAOGFAGBOE-UHFFFAOYSA-N
SMILES C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3
Size 50mg
Supplier Page http://www.selleckchem.com/products/ms-275.html
Additional Information https://file.selleck.cn/downloads/struct/MS-275-Entinostat-chemical-structure-S1053.gif