MS-275 (Entinostat, SNDX-275)
Preferentially inhibits HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 µM). Has no inhibitory activity towards HDAC8 (IC50>100 µM).
| Catalog Number | ABH-012 |
| Alternative Name(s) | Entinostat, SNDX-275 |
| CAS# | 209783-80-2 |
| Inchi | InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26) |
| Inchi Key | INVTYAOGFAGBOE-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3 |
| Size | Inquiry |
| Supplier Page | https://www.agingclocks.com/ms-275-entinostat-sndx-275-item-1427.html |