VH298

VH298 is a potent VHL (Von Hippel-Lindau, the E3 ligase) inhibitor that stabilizes HIF-α. VH298 blocks the VHL:HIF-α interaction with Kd of 90 nM in isothermal titration calorimetry (ITC) and 80 nM in a competitive fluorescence polarization assay. VH-298 can be used in PROTAC technology.

Price Not Available 100mg VH298 Supplier Page

Trivial name	N/A
Catalog Number	S8449
Molecular Formula	C27H33N5O4S
CAS#	2097381-85-4
SMILES	CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)C4(CC4)C#N)O
Size	100mg
Supplier Page	http://www.selleckchem.com/products/vh298.html
Additional Information	https://file.selleck.cn/downloads/struct/s8449-vh298-chemical-structure.gif