Neflamapimod (VX-745)
Neflamapimod (VX-745) is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ.
Trivial name | N/A |
Catalog Number | S1458 |
Molecular Formula | C19H9Cl2F2N3OS |
CAS# | 209410-46-8 |
Inchi | InChI=1S/C19H9Cl2F2N3OS/c20-11-2-1-3-12(21)17(11)18-14-5-7-16(25-26(14)9-24-19(18)27)28-15-6-4-10(22)8-13(15)23/h1-9H |
Inchi Key | VEPKQEUBKLEPRA-UHFFFAOYSA-N |
SMILES | C1=CC(=C(C(=C1)Cl)C2=C3C=CC(=NN3C=NC2=O)SC4=C(C=C(C=C4)F)F)Cl |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/VX-745.html |
Additional Information | https://file.selleck.cn/downloads/struct/VX-745-chemical-structure-S1458.gif |