Uzansertib (INCB053914)

Uzansertib (INCB053914) is a novel, ATP-competitive, small molecule, pan-inhibitor of PIM kinases with IC50 values of 0.24 nM, 30 nM and 0.12 nM for PIM1, PIM2 and PIM3 respectively in biochemical assays.

Price Not Available 1mg Uzansertib (INCB053914) Supplier Page
Trivial name N/A
Catalog Number S8800
Molecular Formula C26H26F3N5O3.H3O4P
CAS# 2088852-47-3
Inchi InChI=1S/C26H26F3N5O3.H3O4P/c1-12-10-34(11-17(30)25(12)36)24-13-5-8-20(35)22(13)31-9-19(24)33-26(37)18-7-6-16(29)23(32-18)21-14(27)3-2-4-15(21)28;1-5(2,3)4/h2-4,6-7,9,12,17,20,25,35-36H,5,8,10-11,30H2 ,1H3,(H,33,37);(H3,1,2,3,4)/t12-,17+,20+,25+;/m0./s1
Inchi Key CYYVLFVRZDZABX-SEDYQSMDSA-N
SMILES CC1CN(CC(C1O)N)C2=C3CCC(C3=NC=C2NC(=O)C4=NC(=C(C=C4)F)C5=C(C=CC=C5F)F)O.OP(=O)(O)O
Size 1mg
Supplier Page http://www.selleckchem.com/products/incb053914.html
Additional Information https://file.selleck.cn/downloads/struct/incb053914-chemical-structure-s8800.gif