Onametostat (JNJ-64619178)

Onametostat (JNJ-64619178) is a PRMT5 inhibitor with high selectivity and potency (subnanomolar range, PRMT5-MEP-50 IC50=0.14 nM) under different in vitro and cellular conditions, paired with favorable pharmacokinetics and safety properties.

Price Not Available 10mM/1mL Onametostat (JNJ-64619178) Supplier Page

Trivial name	N/A
Catalog Number	S8624
Molecular Formula	C22H23BrN6O2
CAS#	2086772-26-9
Inchi	InChI=1S/C22H23BrN6O2/c23-15-8-12-3-1-11(7-16(12)28-21(15)25)2-4-13-9-17(19(31)18(13)30)29-6-5-14-20(24)26-10-27-22(14)29/h1,3,5-8,10,13,17-19,30-31H,2,4,9H2,(H2,25,28)(H2,24,26,27)/t13-,17+,18+,19-/m 0/s1
Inchi Key	DBSMLQTUDJVICQ-CJODITQLSA-N
SMILES	C1C(C(C(C1N2C=CC3=C(N=CN=C32)N)O)O)CCC4=CC5=NC(=C(C=C5C=C4)Br)N
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/jnj-64619178.html
Additional Information	https://file.selleck.cn/downloads/struct/jnj-64619178-chemical-structure-s8624.gif