ZM 336372
ZM 336372 (Zinc00581684) is a potent and selective c-Raf inhibitor with IC50 of 70 nM, 10-fold selectivity over B-RAF, no inhibition to PKA/B/C, AMPK, p70S6, etc.
Trivial name | Zinc00581684 |
Catalog Number | S2720 |
Molecular Formula | C23H23N3O3 |
CAS# | 208260-29-1 |
Inchi | InChI=1S/C23H23N3O3/c1-15-7-10-18(24-23(29)17-5-4-6-19(13-17)26(2)3)14-21(15)25-22(28)16-8-11-20(27)12-9-16/h4-14,27H,1-3H3,(H,24,29)(H,25,28) |
Inchi Key | PYEFPDQFAZNXLI-UHFFFAOYSA-N |
SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)N(C)C)NC(=O)C3=CC=C(C=C3)O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/zm-336372.html |
Additional Information | https://file.selleck.cn/downloads/struct/ZM336372-chemical-structure-s2720.gif |