Casein Kinase inhibitor A86

Casein Kinase inhibitor A86 is a highly effective and orally bioavailable inhibitor of casein kinase 1α (CK1α). Additionally, it displays inhibitory actions towards CDK7 (TFIIH) and CDK9 (P-TEFb). Furthermore, Casein Kinase inhibitor A86 demonstrates the ability to induce apoptosis in leukemia cells, portraying substantial anti-leukemic effects.

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Catalog Number	T39482
Alternative Name(s)	Casein Kinase inhibitor A86
Molecular Formula	C18H25FN6
CAS#	2079069-01-3
SMILES	Cn1ncc(c1CC1CC1)-c1nc(N[C@H]2CC[C@H](N)CC2)ncc1F \|wU:14.15,wD:17.19,(.44,.78,;-.71,-.25,;-2.22,.07,;-2.99,-1.27,;-1.96,-2.41,;-.55,-1.78,;.79,-2.55,;.79,-4.09,;1.56,-5.43,;.02,-5.43,;-2.28,-3.92,;-1.13,-4.95,;-1.45,-6.45,;-.31,-7.48,;-.63,-8.99,;.52,-10.02,;.2,-11.53,;-1.27,-12,;-1.59,-13.51,;-2.41,-10.97,;-2.09,-9.47,;-2.92,-6.93,;-4.06,-5.9,;-3.74,-4.39,;-4.88,-3.36,)\|
Size	1 mg
Supplier Page	https://www.targetmol.com/compound/casein_kinase_inhibitor_a86
Additional Information	https://www.targetmol.com/datasheet/T39482