WEHI-539
WEHI-539 has high affinity (IC50=1.1 nM) and selectivity for BCL-XL and potently kills cells by selectively antagonizing its prosurvival activity. It has more than a 400-fold higher affinity for BCL-XL versus other prosurvival BCL-2 family members.
Catalog Number | S7100 |
Molecular Formula | C31H29N5O3S2 |
CAS# | 1431866-33-9 |
SMILES | C1CC2=C(C=C(C=C2)C3=NC(=C(S3)CCCOC4=CC=C(C=C4)CN)C(=O)O)C(=NNC5=NC6=CC=CC=C6S5)C1.Cl |
Size | 1mg |
Supplier Page | http://www.selleckchem.com/products/wehi-539.html |
Additional Information | https://file.selleck.cn/downloads/struct/wehi-539-chemical-structure-s7100.gif |