IMP-1088
IMP-1088 is a potent dual inhibitor of human N-myristoyltransferases NMT1 and NMT2, with an IC50 of <1 nM for HsNMT1 and HsNMT2 and a Kd of <210 pM for HsNMT1. It effectively inhibits the production of infectious rhinovirus virions by blocking the N-myristoylation of the rhinovirus VP0 protein.
Catalog Number | E0428 |
Molecular Formula | C18H15N3O3S |
CAS# | 2059148-82-0 |
SMILES | CN1C(=O)C(=CC2=C1C=CC(=C2)N[S](=O)(=O)C3=CC=C(C=C3)C#N)C |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/imp-1088.html |
Additional Information | https://file.selleck.cn/downloads/struct/E0428-IMP-1088-chemical-structure.png |