LM2I | MedChemExpress (MCE)
LM2I is a derivative of Spinosyn A (SPA). LM2I is argininosuccinate synthase (ASS1) enzyme activator, and tumor inhibitor that directly interact with ASS1. LM2I has significant antiproliferative activity in seven colorectal cancer cell-lines and xenograft tumors of colorectal cancer. LM2I inhibits colorectal cancer cell growth via the EGFR pathway[1].
Trivial name | LM2I |
Catalog Number | HY-156112 |
Research Area | Cancer |
CAS# | 2055494-50-1 |
Purity | ≥98.00% |
SMILES | O=C(C1=C[C@]2([H])[C@](C=C[C@@]3([H])[C@@]2([H])C[C@H](O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OC)[C@H]4OC)C3)([H])[C@]1([H])C5)[C@H](C)[C@@H](O[C@@H]6O[C@H](C)[C@@H](N(CC(O)CN7CCNCC7)C)CC6)CCC[C@H](CC)OC5=O |
PubChem Chemical Structure ID | 168679851 |
Size | 1 mg |
Supplier Page | https://www.medchemexpress.com/lm2i.html |