Amifostine
Amifostine (WR2721) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer. Amifostine protects cells from damage by scavenging oxygen-derived free radicals. Amifostine reduces renal toxicity and has antiangiogenic action.
| Trivial name | WR2721 |
| Catalog Number | E8201 |
| Molecular Formula | C19H23NO4 |
| CAS# | 20537-88-6 |
| Inchi | InChI=1S/C19H23NO4/c1-20-7-6-19-10-14(21)16(24-3)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19/h4-5,9,12-13,22H,6-8,10H2,1-3H3/t12-,13+,19-/m1/s1 |
| Inchi Key | INYYVPJSBIVGPH-QHRIQVFBSA-N |
| SMILES | CN1CCC23CC(=O)C(=CC2C1CC4=C3C(=C(C=C4)OC)O)OC |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/amifostine-e8201.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e8201-amifostine-chemical-structure-tube.png |