GSK’963
GSK’963 is a chiral small-molecule inhibitor of RIP1 kinase (RIPK1) with an IC50 of 29 nM in FP binding assays. It is >10 000-fold selective for RIP1 over 339 other kinases.
| Trivial name | N/A |
| Catalog Number | S8642 |
| Molecular Formula | C14H18N2O |
| CAS# | 2049868-46-2 |
| Inchi | InChI=1S/C14H18N2O/c1-14(2,3)13(17)16-12(9-10-15-16)11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3/t12-/m0/s1 |
| Inchi Key | NJQVSLWJBLPTMD-LBPRGKRZSA-N |
| SMILES | CC(C)(C)C(=O)N1C(CC=N1)C2=CC=CC=C2 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/gsk963.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gsk963-chemical-structure-s8642.gif |