LLY-283
LLY-283 is a novel and selective inhibitor of protein arginine methyltransferase 5 (PRMT5). LLY-283 inhibits PRMT5 enzymatic activity in vitro and in cells with IC50 of 22 nM and 25 nM, respectively. LLY-283 shows antitumor activity.
Trivial name | N/A |
Catalog Number | S8883 |
Molecular Formula | C17H18N4O4 |
CAS# | 2040291-27-6 |
SMILES | C1=CC=C(C=C1)C(C2C(C(C(O2)N3C=CC4=C(N=CN=C43)N)O)O)O |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/lly-283.html |
Additional Information | https://file.selleck.cn/downloads/struct/s8883-lly-283-chemical-structure.gif |