Laninamivir
Laninamivir(R-125489) is a potent inhibitor of influenza neuraminidase(NA)with IC50s of 0.90 nM, 1.83 nM and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI/5+/1957 H2N2 N2 (p57N2), respectively. It exhibits long-acting anti-influenza virus activity.
Trivial name | R-125489 |
Catalog Number | E4879 |
Molecular Formula | C22H24FN5O4 |
CAS# | 203120-17-6 |
Inchi | InChI=1S/C22H24FN5O4/c1-11-7-15-16(27-11)5-6-17(19(15)23)32-21-20-13(3)18(8-28(20)26-10-25-21)30-9-12(2)31-22(29)14(4)24/h5-8,10,12,14,27H,9,24H2,1-4H3/t12-,14+/m1/s1 |
Inchi Key | LTEJRLHKIYCEOX-OCCSQVGLSA-N |
SMILES | CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OCC(C)OC(=O)C(C)N)C |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/laninamivir.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4879-Laninamivir-chemical-structure.png |