JANEX-1
JANEX-1 (WHI-P131) is a small molecule inhibitor of JAK3 that selectively inhibits JAK3 at an IC50 of 78 µM without altering the activity of JAK1 or JAK2, or any other protein tyrosine kinases (IC50 ≥ 350 µM).
| Trivial name | WHI-P131 |
| Catalog Number | S5903 |
| Molecular Formula | C16H15N3O3 |
| CAS# | 202475-60-3 |
| Inchi | InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19) |
| Inchi Key | HOZUXBLMYUPGPZ-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/janex-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/janex-1-chemical-structure-s5903.gif |