Deferasirox
Deferasirox is an iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor. Deferasirox-induced iron depletion promotes BclxL downregulation and cell death.
| Trivial name | CGP-72670, ICL-670 |
| Catalog Number | S1712 |
| Molecular Formula | C31H38N6O2 |
| CAS# | 201530-41-8 |
| Inchi | InChI=1S/C31H38N6O2/c1-6-22(5)37-18-20(3)29-25(30(38)34-17-26-19(2)13-21(4)35-31(26)39)14-24(15-27(29)37)23-7-8-28(33-16-23)36-11-9-32-10-12-36/h7-8,13-16,18,22,32H,6,9-12,17H2,1-5H3,(H,34,38)(H,35,39 )/t22-/m0/s1 |
| Inchi Key | FKSFKBQGSFSOSM-QFIPXVFZSA-N |
| SMILES | CCC(C)N1C=C(C2=C(C=C(C=C21)C3=CN=C(C=C3)N4CCNCC4)C(=O)NCC5=C(C=C(NC5=O)C)C)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/Deferasirox(Exjade).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Deferasirox-Exjade-chemical-structure-S1712.gif |