Deferasirox
Deferasirox is an iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor. Deferasirox-induced iron depletion promotes BclxL downregulation and cell death.
| Trivial name | CGP-72670, ICL-670 |
| Catalog Number | S1712 |
| Molecular Formula | C21H15N3O4 |
| CAS# | 201530-41-8 |
| Inchi | InChI=1S/C21H15N3O4/c25-17-7-3-1-5-15(17)19-22-20(16-6-2-4-8-18(16)26)24(23-19)14-11-9-13(10-12-14)21(27)28/h1-12,25-26H,(H,27,28) |
| Inchi Key | BOFQWVMAQOTZIW-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C(=C1)C2=NN(C(=N2)C3=CC=CC=C3O)C4=CC=C(C=C4)C(=O)O)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Deferasirox(Exjade).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Deferasirox-Exjade-chemical-structure-S1712.gif |