Lenumlostat
Lenumlostat (PAT-1251, GB2064) is a potent, selective, and orally available inhibitor of lysyl oxidase-like 2 (LOXL2). It exhibits greater selectivity for LOXL2 over other family members, with IC50 of 0.71 μM for hLOXL2 and 1.17 μM for hLOXL3. It also possesses anti-fibrotic properties.
| Trivial name | PAT-1251; GB2064 |
| Catalog Number | E5824 |
| Molecular Formula | C5H4N4S |
| CAS# | 2007885-39-2 |
| Inchi | InChI=1S/C5H4N4S/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10) |
| Inchi Key | GLVAUDGFNGKCSF-UHFFFAOYSA-N |
| SMILES | C1=NC2=C(N1)C(=S)N=CN2 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/lenumlostat.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5824-Lenumlostat-chemical-structure.png |