Lenumlostat
Lenumlostat (PAT-1251, GB2064) is a potent, selective, and orally available inhibitor of lysyl oxidase-like 2 (LOXL2). It exhibits greater selectivity for LOXL2 over other family members, with IC50 of 0.71 μM for hLOXL2 and 1.17 μM for hLOXL3. It also possesses anti-fibrotic properties.
| Trivial name | PAT-1251; GB2064 |
| Catalog Number | E5824 |
| Molecular Formula | C8H15N3O7 |
| CAS# | 2007885-39-2 |
| Inchi | InChI=1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1 |
| Inchi Key | ZSJLQEPLLKMAKR-GKHCUFPYSA-N |
| SMILES | CN(C(=O)NC1C(C(C(OC1O)CO)O)O)N=O |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/lenumlostat.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5824-Lenumlostat-chemical-structure.png |