GMX1778
GMX1778 is a potent and specific inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) with IC50 and Kd of < 25 nM and 120 nM, respectively. GMX1778 induces programmed cell death with apoptotic features. Phase 1.
| Trivial name | CHS828 |
| Catalog Number | S8117 |
| Molecular Formula | C19H22ClN5O |
| CAS# | 200484-11-3 |
| Inchi | InChI=1S/C19H22ClN5O/c20-16-5-7-18(8-6-16)26-14-4-2-1-3-11-23-19(24-15-21)25-17-9-12-22-13-10-17/h5-10,12-13H,1-4,11,14H2,(H2,22,23,24,25) |
| Inchi Key | BOIPLTNGIAPDBY-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1OCCCCCCN=C(NC#N)NC2=CC=NC=C2)Cl |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/gmx1778-chs828.html |
| Additional Information | https://file.selleck.cn/downloads/struct/chs828-gmx1778-chemical-structure-s8117.gif |