(R)-GNE-140
(R)-GNE-140 is a selective inhibitor of the LDHA and LDHB with IC50s of 3 nM and 5 nM, respectively. The R enantiomer of GNE-140 is 18-fold more potent than S enantiomer.
| Trivial name | N/A |
| Catalog Number | S6675 |
| Molecular Formula | C25H23ClN2O3S2 |
| CAS# | 2003234-63-5 |
| Inchi | InChI=1S/C25H23ClN2O3S2/c26-20-3-1-2-4-22(20)33-23-21(29)15-25(27-24(23)30,18-9-14-32-16-18)17-5-7-19(8-6-17)28-10-12-31-13-11-28/h1-9,14,16,29H,10-13,15H2,(H,27,30)/t25-/m1/s1 |
| Inchi Key | SUFXXEIVBZJOAP-RUZDIDTESA-N |
| SMILES | C1COCCN1C2=CC=C(C=C2)C3(CC(=C(C(=O)N3)SC4=CC=CC=C4Cl)O)C5=CSC=C5 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/r-gne-140.html |
| Additional Information | https://file.selleck.cn/downloads/struct/r-gne-140-chemical-structure-s6675.gif |