Bavdegalutamide (ARV-110)
Bavdegalutamide (ARV-110) is an orally bioavailable, specific androgen receptor (AR) PROTAC degrader that leads to ubiquitination and degradation of AR. ARV-110 completely degrades androgen receptor (AR) in all cell lines tested with DC50 of < 1 nM. ARV-110 can be used for the research of prostate cancer.
| Trivial name | N/A |
| Catalog Number | S6965 |
| Molecular Formula | C41H43ClFN9O6 |
| CAS# | 2222112-77-6 |
| SMILES | FC1=CC2=C(C=C1N3CCN(CC3)CC4CCN(CC4)C5=NN=C(C=C5)C(=O)NC6CCC(CC6)OC7=CC=C(C#N)C(=C7)Cl)C(=O)N(C8CCC(=O)NC8=O)C2=O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/arv-110.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s6965-arv-110-chemical-structure.gif |