Tolebrutinib
Tolebrutinib is an oral, CNS-penetrant, irreversible inhibitor of Bruton’s tyrosine kinase (BTK) with IC50s of 0.4 nM and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively.
| Trivial name | SAR442168, PRN2246 |
| Catalog Number | E0041 |
| Molecular Formula | C₂₆H₂₅N₅O₃ |
| CAS# | 1971920-73-6 |
| SMILES | NC1=NC=CC2=C1N(C(=O)N2C3CCCN(C3)C(=O)C=C)C4=CC=C(OC5=CC=CC=C5)C=C4 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/tolebrutinib-sar442168.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e0041-tolebrutinib-chemical-structure.gif |