(R)-Nepicastat HCl
(R)-Nepicastat HCl (RS-25560-198), the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
Trivial name | RS-25560-198 HCl |
Catalog Number | S4926 |
Molecular Formula | C14H15F2N3S.HCl |
CAS# | 195881-94-8 |
Inchi | InChI=1S/C14H15F2N3S.ClH/c15-9-3-8-4-10(1-2-12(8)13(16)5-9)19-11(6-17)7-18-14(19)20;/h3,5,7,10H,1-2,4,6,17H2,(H,18,20);1H/t10-;/m1./s1 |
Inchi Key | DIPDUAJWNBEVOY-HNCPQSOCSA-N |
SMILES | C1CC2=C(CC1N3C(=CNC3=S)CN)C=C(C=C2F)F.Cl |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/r-nepicastat-hcl.html |
Additional Information | https://file.selleck.cn/downloads/struct/R-Nepicastat-HCl-chemical-structure-s4926.gif |