KY 12420
KY 12420 is the first described PI3K inhibitor with IC50 of 3 nM in a cell-free assay, with little selectivity within the PI3K family. It also blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM in cell-free assays.
| Trivial name | SL-2052;Wortmannin;SL-2052 |
| Catalog Number | CSN12216 |
| Alternative Name(s) | SL-2052;Wortmannin;SL-2052 |
| Research Area | Cancer |
| Molecular Formula | C23H24O8 |
| CAS# | 19545-26-7 |
| Purity | ≥99% |
| SMILES | CC(O[C@@H](C1=C2C(C3=C4C(C(O[C@H](COC)[C@]14C)=O)=CO3)=O)C[C@]5(C)C(CC[C@]52[H])=O)=O |
| Size | 1mg |
| Supplier Page | https://www.csnpharm.com/products/wortmannin.html |