BAY 11-7082
BAY 11-7082 (BAY 11-7821) is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM in tumor cells. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 with IC50 of 0.19 μM and 0.96 μM, respectively. BAY 11-7082 induces apoptosis and S phase arrest in gastric cancer cells.
| Trivial name | BAY 11-7821 |
| Catalog Number | S2913 |
| Molecular Formula | C14H14N4O3 |
| CAS# | 19542-67-7 |
| Inchi | InChI=1S/C14H14N4O3/c1-7-16-9-4-2-3-8(15)12(9)14(21)18(7)10-5-6-11(19)17-13(10)20/h2-4,10H,5-6,15H2,1H3,(H,17,19,20) |
| Inchi Key | RSNPAKAFCAAMBH-UHFFFAOYSA-N |
| SMILES | CC1=NC2=CC=CC(=C2C(=O)N1C3CCC(=O)NC3=O)N |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/bay-11-7082-bay-11-7821.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s2913-bay-11-7082-chemical-structure.png |