R121919
R121919 (NBI30775) is a potent and selective CRF1R antagonist with a Ki of 2 to 5 nM. R121919 has antidepressant and anxiolytic effects. R121919 alleviates defensive withdrawal in rats.
| Trivial name | NBI30775 |
| Catalog Number | E7586 |
| Molecular Formula | C28H38F3N5O2.C4H6O5 |
| CAS# | 195055-03-9 |
| SMILES | COCC(N1CCN(CC1C)C2(C)CCN(CC2)C(=O)C3=C(C)N=CN=C3C)C4=CC=C(C=C4)C(F)(F)F.OC(CC(O)=O)C(O)=O |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/r121919.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7586-r121919-chemical-structure-tube.png |