ARV-771
ARV-771 is a potent pan-(bromodomain and extra-terminal)BET degrader, a novel BET-PROTAC(proteolysis-targeting chimera) with Kd of 34 nM, 4.7 nM, 8.3 nM, 7.6 nM, 9.6 nM, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1), and BRD4(2), respectively.
| Trivial name | N/A |
| Catalog Number | S8532 |
| Molecular Formula | C49H60ClN9O7S2 |
| CAS# | 1949837-12-0 |
| SMILES | CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NCCOCCCOCC(=O)NC(C(=O)N4CC(CC4C(=O)NC(C)C5=CC=C(C=C5)C6=C(N=CS6)C)O)C(C)(C)C)C7=CC=C(C=C7)Cl)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/arv-771.html |
| Additional Information | https://file.selleck.cn/downloads/struct/arv-771-chemical-structure-s8532.gif |