Semaxanib (SU5416)

Semaxanib (SU5416, semaxinib) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR. Phase 3.

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Trivial name	semaxinib
Catalog Number	S2845
Molecular Formula	C15H14N2O
CAS#	204005-46-9
Inchi	InChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)/b12-8-
Inchi Key	WUWDLXZGHZSWQZ-WQLSENKSSA-N
SMILES	CC1=CC(=C(N1)C=C2C3=CC=CC=C3NC2=O)C
Size	5mg
Supplier Page	http://www.selleckchem.com/products/semaxanib-su5416.html
Additional Information	https://file.selleck.cn/downloads/struct/Semaxanib-chemical-structure-s2845.gif