Lonafarnib (SCH66336)
Lonafarnib (SCH66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM in cell-free assays, respectively. Phase 3.
| Trivial name | N/A |
| Catalog Number | S2797 |
| Molecular Formula | C15H22N2. 2HCl |
| CAS# | 193275-84-2 |
| Inchi | InChI=1S/C15H22N2.2ClH/c16-12-6-8-13(9-7-12)17-15-10-14(15)11-4-2-1-3-5-11;;/h1-5,12-15,17H,6-10,16H2;2*1H/t12?,13?,14-,15+;;/m0../s1 |
| Inchi Key | UCINOBZMLCREGM-RNNUGBGQSA-N |
| SMILES | C1CC(CCC1N)NC2CC2C3=CC=CC=C3.Cl.Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/lonafarnib-sch66336.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Lonafarnib-chemical-structure-s2797.gif |