Lonafarnib (SCH66336)

Lonafarnib (SCH66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM in cell-free assays, respectively. Phase 3.

Price Not Available 10mM/1mL Lonafarnib (SCH66336) Supplier Page

Trivial name	N/A
Catalog Number	S2797
Molecular Formula	C27H31Br2ClN4O2
CAS#	193275-84-2
Inchi	InChI=1S/C27H31Br2ClN4O2/c28-20-12-19-2-1-18-13-21(30)14-22(29)24(18)25(26(19)32-15-20)17-5-9-33(10-6-17)23(35)11-16-3-7-34(8-4-16)27(31)36/h12-17,25H,1-11H2,(H2,31,36)/t25-/m1/s1
Inchi Key	DHMTURDWPRKSOA-RUZDIDTESA-N
SMILES	C1CN(CCC1CC(=O)N2CCC(CC2)C3C4=C(CCC5=C3N=CC(=C5)Br)C=C(C=C4Br)Cl)C(=O)N
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/lonafarnib-sch66336.html
Additional Information	https://file.selleck.cn/downloads/struct/Lonafarnib-chemical-structure-s2797.gif