Linrodostat (BMS-986205)

Linrodostat (BMS-986205, ONO-7701) is an irreversible inhibitor of IDO1 with an IC50 of 1.7 nM. It inhibits kynurenine production with IC50 values of 1.7, 1.1 and > 2000 in human HeLa, HEK293 expressing human IDO-1 and tryptophan-2, 3-dioxygenase cell-based assays.

Price Not Available 25mg Linrodostat (BMS-986205) Supplier Page

Trivial name	ONO-7701
Catalog Number	S8629
Molecular Formula	C24H24ClFN2O
CAS#	1923833-60-6
Inchi	InChI=1S/C24H24ClFN2O/c1-15(24(29)28-20-9-6-18(25)7-10-20)16-2-4-17(5-3-16)21-12-13-27-23-11-8-19(26)14-22(21)23/h6-17H,2-5H2,1H3,(H,28,29)/t15-,16-,17+/m1/s1
Inchi Key	KRTIYQIPSAGSBP-ZACQAIPSSA-N
SMILES	CC(C1CCC(CC1)C2=C3C=C(C=CC3=NC=C2)F)C(=O)NC4=CC=C(C=C4)Cl
Size	25mg
Supplier Page	http://www.selleckchem.com/products/bms-986205.html
Additional Information	https://file.selleck.cn/downloads/struct/bms-986205-chemical-structure-s8629.gif