Pomalidomide
Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. Pomalidomide can be utilized in PROTAC as a ligand for targeting E3 ligase and inhibiting the E3 ligase protein cereblon (CRBN). Pomalidomide promotes apoptosis and cell cycle arrest.
| Trivial name | CC-4047 |
| Catalog Number | S1567 |
| Molecular Formula | C14H14O3 |
| CAS# | 19171-19-8 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | OC1=CC=C(CCC2=CC(=CC(=C2)O)O)C=C1 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Pomalidomide(CC-4047).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Pomalidomide-chemical-structure-S1567.gif |