Danicopan
Danicopan is a potent, selective and orally active inhibitor of factor D with Kd of 0.54 nM for human Factor D. Danicopan inhibits alternative pathway of complement (APC) activity, and has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).
| Trivial name | ACH-4471, ACH-0144471, ACH-CFDIS, ALXN 2040 |
| Catalog Number | S0803 |
| Molecular Formula | C26H23BrFN7O3 |
| CAS# | 1903768-17-1 |
| SMILES | CC1=NC=C(C=N1)C2=CC3=C(C=C2)N(N=C3C(=O)C)CC(=O)N4CC(CC4C(=O)NC5=NC(=CC=C5)Br)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/danicopan.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s0803-danicopan-chemical-structure.gif |