CHZ868
CHZ868 is an inhibitor of type II JAK2 with an IC50 value of 0.17 μM in EPOR JAK2 WT Ba/F3 cells. CHZ868 demonstrates 60- to 70-fold higher inhibition of JAK1-/TYK2-mediated nuclear STAT1 translocation compared to pan-JAK inhibitors.
| Catalog Number | S7899 |
| CAS# | 1895895-38-1 |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/chz868.html |
| Additional Information | https://file.selleck.cn/downloads/struct/S7899-CHZ868-chemical-structure.png |