Gamcemetinib (CC-99677)
Gamcemetinib (CC-99677,BMS-986371) is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) (MAPKAPK2 (MK2)) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM).
Trivial name | BMS-986371 |
Catalog Number | E1657 |
Molecular Formula | C22H20ClN5O3S |
CAS# | 1887069-10-4 |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/cc-99677.html |
Additional Information | https://file.selleck.cn/downloads/struct/e1657-CC-99677-chemical-structure.png |