LMP517 | MedChemExpress (MCE)
LMP517 (NSC 781517) a indenoisoquinoline, is a potent a dual TOP1 and TOP2 inhibitor. LMP517 shows better antitumor activity than its parent compound LMP744 (HY-U00248) against H82 (Small Cell Lung Cancer) xenografts. LMP517 induces TOP1 cleavage complexes (TOP1ccs) and TOP2ccs[1].
| Trivial name | LMP517 |
| Catalog Number | HY-160005 |
| Alternative Name(s) | NSC 781517 |
| Research Area | Cancer |
| CAS# | 1883730-99-1 |
| Purity | ≥98.00% |
| SMILES | O=C1C2=CC3=C(C=C2C4=C1C5=C(C(N4CCCNCCO)=O)C=C(F)C=C5)OCO3 |
| PubChem Chemical Structure ID | 122484905 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/lmp517.html |