AMG PERK 44
AMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) and induces autophagy. It has 1000-fold and 160-fold selectivity over GCN2 (IC50: 7300 nM) and B-Raf (IC50 >1000 nM), respectively.

Catalog Number | T10299 |
Research Area | MAPK |
Molecular Formula | C34H29ClN4O2 |
CAS# | 1883548-84-2 |
SMILES | Cl.O=C(C1=CC=C(C(C2=CC=C3N=C(C=CC3=C2)C)=C1N)C)C=4C(=O)N(C=5C=CC=CC5)N(C4C=6C=CC=CC6)C |
Size | 50 mg |
Supplier Page | https://www.targetmol.com/compound/AMG PERK 44 |
Additional Information | https://www.targetmol.com/datasheet/T10299 |