Roscovitine
Roscovitine is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM in cell-free assays. It shows little effect on CDK4/6. Phase 2.
| Trivial name | CYC202, Seliciclib, R-roscovitine |
| Catalog Number | S1153 |
| Molecular Formula | C19H26N6O |
| CAS# | 186692-46-6 |
| Inchi | InChI=1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m1/s1 |
| Inchi Key | BTIHMVBBUGXLCJ-OAHLLOKOSA-N |
| SMILES | CCC(CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Roscovitine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Roscovitine-Seliciclib-chemical-structure-S1153.gif |