Roscovitine
Roscovitine is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM in cell-free assays. It shows little effect on CDK4/6. Phase 2.
| Trivial name | CYC202, Seliciclib, R-roscovitine |
| Catalog Number | S1153 |
| Molecular Formula | C7H5Cl2NO4S |
| CAS# | 186692-46-6 |
| Inchi | InChI=1S/C7H5Cl2NO4S/c8-10(9)15(13,14)6-3-1-5(2-4-6)7(11)12/h1-4H,(H,11,12) |
| Inchi Key | XPDVQPODLRGWPL-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C(=O)O)S(=O)(=O)N(Cl)Cl |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/Roscovitine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Roscovitine-Seliciclib-chemical-structure-S1153.gif |