Zibotentan (ZD4054)
Zibotentan (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.
Trivial name | N/A |
Catalog Number | S1456 |
Molecular Formula | C15H12N2O7 |
CAS# | 186497-07-4 |
Inchi | InChI=1S/C15H12N2O7/c18-10-5-4-8(13(21)16-10)17-14(22)7-2-1-3-9(12(7)15(17)23)24-6-11(19)20/h1-3,8H,4-6H2,(H,19,20)(H,16,18,21) |
Inchi Key | ZVWIXIGBWIEDFO-UHFFFAOYSA-N |
SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/Zibotentan(ZD4054).html |
Additional Information | https://file.selleck.cn/downloads/struct/Zibotentan-ZD4054-chemical-structure-S1456.gif |