(E)-3PO

(E)-3PO is a small-molecule inhibitor of the PFKFB3 isozyme, 3PO markedly attenuates the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines (IC50, 1.4-24 μM) which target: PFKFB3 isozyme. 3PO inhibits recombinant PFKFB3 activity, suppresses glucose uptake, and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+, and NADH in vitro.

Price Not Available 25mg (E)-3PO Supplier Page
Trivial name (E)-3-PO
Catalog Number CSN13880
Alternative Name(s) (E)-3-PO
Research Area Cancer
Molecular Formula C13H10N2O
CAS# 18550-98-6
Purity ≥98%
SMILES O=C(C1=CC=NC=C1)/C=C/C2=CC=CN=C2
Size 25mg
Supplier Page https://www.csnpharm.com/products/(e)-3po.html