Etanercept
Etanercept, a dimeric fusion protein, functions as an inhibitor of TNF by binding to TNF. It competitively blocks the attachment of both TNF-α and TNF-β to their cell surface receptors, thereby neutralizing TNF’s biological activity. Etanercept has proven effectiveness in treating rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis.
| Catalog Number | P1240 |
| Molecular Formula | C22H25FN4O2.H3O4P |
| CAS# | 185243-69-0 |
| Inchi | InChI=1S/C22H25FN4O2.H3O4P/c1-13-19(12-17-16-11-15(23)5-6-18(16)26-21(17)28)25-14(2)20(13)22(29)24-7-10-27-8-3-4-9-27;1-5(2,3)4/h5-6,11-12,25H,3-4,7-10H2,1-2H3,(H,24,29)(H,26,28);(H3,1,2,3,4)/b17-12-; |
| Inchi Key | AOORBROPMMRREB-HBPAQXCTSA-N |
| SMILES | CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)C=C3C4=C(C=CC(=C4)F)NC3=O.OP(=O)(O)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/etanercept.html |
| Additional Information | https://file.selleck.cn/downloads/struct/P1240-Etanercept-chemical-structure-tube.png |