Etanercept
Etanercept, a dimeric fusion protein, functions as an inhibitor of TNF by binding to TNF. It competitively blocks the attachment of both TNF-α and TNF-β to their cell surface receptors, thereby neutralizing TNF’s biological activity. Etanercept has proven effectiveness in treating rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis.
Catalog Number | P1240 |
Molecular Formula | C22H28O3 |
CAS# | 185243-69-0 |
Inchi | InChI=1S/C22H28O3/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21)12-8-19(24)25-22/h3-4,13,16-18H,5-12H2,1-2H3/t16-,17+,18+,20+,21+,22-/m1/s1 |
Inchi Key | UJVLDDZCTMKXJK-WNHSNXHDSA-N |
SMILES | CC12CCC(=O)C=C1C=CC3C2CCC4(C3CCC45CCC(=O)O5)C |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/etanercept.html |
Additional Information | https://file.selleck.cn/downloads/struct/P1240-Etanercept-chemical-structure-tube.png |