Tomivosertib (eFT-508)
Tomivosertib (eFT-508) is a potent and selective MNK1/2 inhibitor with IC50s of 2.4 nM and 1 nM, respectively. It potentially results in decreased tumor cell proliferation and tumor growth. Tomivosertib (eFT-508) inhibits eIF4E phosphorylation and dramatically downregulates PD-L1 protein abundance.
| Trivial name | N/A |
| Catalog Number | S8275 |
| CAS# | 1849590-01-7 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/eft-508.html |
| Additional Information | https://file.selleck.cn/downloads/struct/eft-508-chemical-structure-s8275.gif |