Tomivosertib (eFT-508)

Tomivosertib (eFT-508) is a potent and selective MNK1/2 inhibitor with IC50s of 2.4 nM and 1 nM, respectively. It potentially results in decreased tumor cell proliferation and tumor growth. Tomivosertib (eFT-508) inhibits eIF4E phosphorylation and dramatically downregulates PD-L1 protein abundance.

Price Not Available 25mg Tomivosertib (eFT-508) Supplier Page
Trivial name N/A
Catalog Number S8275
Molecular Formula C17H20N6O2
CAS# 1849590-01-7
Inchi InChI=1S/C17H20N6O2/c1-10-7-11(21-13-8-12(18)19-9-20-13)16(25)23-14(10)15(24)22-17(23)5-3-2-4-6-17/h7-9H,2-6H2,1H3,(H,22,24)(H3,18,19,20,21)
Inchi Key HKTBYUWLRDZAJK-UHFFFAOYSA-N
SMILES CC1=C2C(=O)NC3(N2C(=O)C(=C1)NC4=NC=NC(=C4)N)CCCCC3
Size 25mg
Supplier Page http://www.selleckchem.com/products/eft-508.html
Additional Information https://file.selleck.cn/downloads/struct/eft-508-chemical-structure-s8275.gif