Gefitinib hydrochloride
Gefitinib (ZD1839) is an EGFR inhibitor with IC50s of 15.5 nM and 823.3 nM for WT EGFR and EGFR (858R/T790M), respectively.
Trivial name | ZD1839 hydrochloride |
Catalog Number | S5098 |
Molecular Formula | C22H24ClFN4O3.HCl |
CAS# | 184475-55-6 |
Inchi | InChI=1S/C22H24ClFN4O3.ClH/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15;/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27);1H |
Inchi Key | QUINXWLATMJDQF-UHFFFAOYSA-N |
SMILES | COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4.Cl |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/gefitinib-hydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/gefitinib-hydrochloride-chemical-structure-s5098.gif |