TH 1020
TH1020 is Toll-like receptor (TLR) 5/Flagellin complex antagonist with IC50 of 0.85 μM. TH1020 competes with flagellin for TLR5 binding to inhibit the TLR5:flagellin interaction and subsequent downstream TNF-α secretion.
| Trivial name | / |
| Catalog Number | CSN27285 |
| Alternative Name(s) | / |
| Research Area | Immunology/Inflammation |
| Molecular Formula | C23H15N7S2 |
| CAS# | 1841460-82-9 |
| Purity | ≥98% |
| SMILES | C12=NC=NC(SC3=NN=C(C4=CC=NC=C4)N3CC5=CC=CC=C5)=C1SC6=NC=CC=C62 |
| Size | 10mg |
| Supplier Page | https://www.csnpharm.com/products/4-((4-benzyl-5-(pyridin-4-yl)-4h-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine.html |